Introduction
Dr. Bryant Lin, a Stanford medical professor, teaches a lung cancer class in the fall of 2024. Initially nervous, he shares his story with students.
The Irony and Hope of Advocacy
Lin founded the Center for Asian Health Research and Education at Stanford, advocating for improved lung cancer screenings. Ironically, two years ago, Lin became a Stage IV lung cancer patient himself. Although a non-smoker, he remains hopeful due to advancements in personalized and specialized therapeutics.
“If we’re not able to cure lung cancer, we can at least turn it into a chronic disease.” – Dr. Bryant Lin
The prognosis for lung cancer is changing, with survival rates improving. The overall five-year survival rate has doubled in three decades to 30%.
Targeted Treatment Advances
Lung cancers are genetically diverse, complicating treatment. Genetic testing identifies specific mutations, allowing targeted therapies that shrink tumors with fewer side effects. UCLA oncologist Jonathan Goldman emphasizes the importance of genetic testing, which is not yet standard for all U.S. lung cancer patients.
Goldman’s research, published in the New England Journal of Medicine, shows reduced recurrence with targeted medicines. Dr. Lin began treatment with Tagrisso, a targeted drug approved by the FDA.
Challenges with Affordability and Access
Targeted cancer treatments are expensive, causing battles with insurance companies for coverage. Lin experienced delays due to insurance issues with a $16,000 drug.
Regulatory approval brought new drug combinations like amivantamab and lazertinib, providing Lin better quality of life. He continues teaching and advising on lung cancer.
Potential Crossover with Other Cancers
Recent breakthroughs may apply to lung cancer. FDA-approved drugs for pancreatic cancer may offer potential crossover. Personalized mRNA vaccines show promise in engaging the immune system against tumors.
Advancements in AI imaging and blood tests could improve screening rates and early detection. Dr. Lin advocates for broader screening technologies beyond the traditional CT scan.
Living While Fighting Cancer
Lin shares from another patient: survival means waiting for the next treatment. His life involves balancing optimism and realism.
Despite setbacks, he enjoys time with family, catching baseball games, and tinkering with a typewriter for his upcoming book, “Sunshine.” He values the importance of a little silliness in life.
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