Infections caused by the Cyclospora parasite are increasing sharply in the United States. Reports from over 30 states indicate that 2026 is set to be the worst year yet for cases of this diarrhea-inducing ailment. As of now, reported infections have already surpassed 2019’s record of approximately 4,700 cases.
Though typically not life-threatening, cyclosporiasis is commonly treated with antibiotics. Officials have not pinpointed the exact source of the surge. However, infections in at least four states—Michigan, Ohio, Kentucky, and West Virginia—seem to be connected.
Michigan’s Lettuce Link
There have been more than 3,300 reported cases in Michigan. According to Natasha Bagdasarian, the state’s health department’s chief medical executive, early investigations suggest that lettuce or salad greens might be contributing factors. After interviewing over 1,000 patients, lettuce appeared frequently as a common item.
Given this potential link and past cyclospora outbreaks caused by produce, Michigan officials recommend buying whole lettuce heads, discarding the outer leaves, and thoroughly washing the remaining leaves. Consumers should avoid bagged lettuce and pre-packaged salad kits.
Buy whole heads of lettuce, discard the outer layers, and wash thoroughly.
Taco Bell has responded by voluntarily and temporarily removing certain ingredients at select locations as a precaution.
The Broader Investigation
Federal health officials continue to investigate various produce items. Donald Prater, Acting Deputy Commissioner for Food at the U.S. Food and Drug Administration, stated that traceback investigations are ongoing.
Cyclospora is a small parasite known for causing explosive diarrhea. It spreads through fecally-contaminated water and has previously been linked to contaminated fruits and vegetables.
Cyclosporiasis is less common than other foodborne illnesses like salmonella and E. coli. The illness has, however, been on the rise for a decade. This increase is attributed to improved detection and potentially climate change.
Current Data and Expectations
2019 was previously the most severe year for cyclospora infections in the U.S., with about 4,700 reported cases. The Centers for Disease Control and Prevention (CDC) reported over 1,600 confirmed cases and over 5,100 pending analysis since May 1, 2026.
The true number of cases could be higher, given that some may not seek medical care for milder symptoms. It takes days or weeks for symptoms to develop after exposure, and officials expect case numbers to rise through August.
Reports come from 34 states, with no deaths recorded. Michigan, Ohio, New York City, and Illinois have seen significant numbers of cases. Only some of these infections can be tied to a singular source, with travel being a factor in Illinois. In Michigan, a domestic outbreak connection is suspected.
CDC officials are still investigating the precise reasons for Michigan, Ohio, Kentucky, and West Virginia appearing to share an outbreak.
The Associated Press Health and Science Department, backed by the Howard Hughes Medical Institute’s Department of Science Education and the Robert Wood Johnson Foundation, remains the sole source of content. Associated Press writer Dee-Ann Durbin contributed to this report from Detroit.
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